Better Menopause Care Begins With Asking

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Better Menopause Care Begins With Asking

New national guidance gives clinicians a clearer path to treat hot flashes, sleep loss, and mood changes. Here is what it means for patients and the physicians who care for them.

October 2026

Menopause symptoms are common, disruptive, and treatable. Too many women still live with them without a plan.

On October 15, 2026, the American College of Obstetricians and Gynecologists (ACOG) published Clinical Practice Guideline No. 13, Management of Menopause-Related Vasomotor, Sleep, and Mood Symptoms. It replaces guidance from 2014 and covers hormonal, nonhormonal, and nonpharmacologic treatment.

For the American College of Osteopathic Obstetricians and Gynecologists (ACOOG), the guideline reinforces a principle osteopathic physicians practice every day. Treat the whole person. Ask about every symptom. Offer every evidence-based option.

50% to 92%

of women in menopause report hot flashes or night sweats.

16% to 66%

of women in the United States report sleep disruption tied to menopause.

About 36%

of perimenopausal and postmenopausal women worldwide report depressive symptoms.

Source: ACOG Clinical Practice Guideline No. 13, 2026.

Start the conversation earlier

Many patients never mention their symptoms. Some assume nothing helps. Others hear their symptoms dismissed as part of aging.

The guideline calls for earlier and more complete patient education so women recognize perimenopause and seek care sooner. Physicians set the tone. Ask every midlife patient about hot flashes, sleep, and mood at each annual visit, and treat the answers as clinical information worth acting on.

Put hormone therapy back on the table

The guideline strongly recommends systemic menopausal hormone therapy (MHT) for hot flashes, night sweats, and related sleep disruption in patients without contraindications. Patients with a uterus need estrogen plus a progestogen. Patients without a uterus use estrogen alone.

Timing matters. When a patient chooses MHT, the guideline recommends starting before age 60 or within 10 years of natural menopause. After this window, baseline risks of blood clots, stroke, and coronary heart disease rise, and the decision calls for an individualized approach.

Outdated fears still steer many of these decisions. In 2025, the U.S. Food and Drug Administration (FDA) recommended removing boxed warnings for cardiovascular disease, breast cancer, and probable dementia from MHT labeling. The guideline also notes nearly two-thirds of Women's Health Initiative participants were 60 or older, which limits how well those findings apply to younger women near menopause. Shared decision-making, grounded in each patient's age, history, risks, and goals, leads the way.

Practice points for patients on MHT

  • Check effectiveness and tolerability at 3 months, then every 12 months.
  • Evaluate for endometrial pathology when bleeding occurs or continues past the first 6 months.
  • Individualize when and how to stop, and counsel patients about symptom return.
  • Continue to assess contraception needs until age 55.

Effective options without hormones

Some patients have contraindications. Others prefer to avoid hormones. Every patient deserves an effective treatment, and the guideline outlines several.

Neurokinin receptor antagonists

Strongly recommended. Fezolinetant and elinzanetant act on the brain's temperature control center. Elinzanetant also shows sleep benefit. Both require liver function monitoring.

SSRIs and SNRIs

Strongly recommended for hot flashes and depressive symptoms together. Low-dose paroxetine is the only antidepressant FDA-approved for hot flashes. Avoid fluoxetine and paroxetine with tamoxifen.

Gabapentin

Suggested when other nonhormonal options fail or cause side effects. Bedtime dosing supports sleep and limits daytime drowsiness.

Care for the whole person

The guideline conditionally recommends cognitive behavioral therapy (CBT), mindfulness-based interventions, exercise, clinical hypnosis, and acupuncture for vasomotor, sleep, and mood symptoms. It generally pairs these approaches with medication.

This approach fits the osteopathic model of care. Sleep, movement, stress, and mood affect one another. A treatment plan built around all four serves the patient better than a prescription alone.

Ask patients what they already take

The evidence does not support soy isoflavones, other phytoestrogens, or herbal supplements for menopause symptoms. These products reach patients through heavy marketing, and the FDA does not test them for safety, effectiveness, or purity. The guideline also does not support progestogen alone, dehydroepiandrosterone (DHEA), or testosterone for these symptoms.

Close the gaps in care

Access to menopause care remains uneven. In the Study of Women's Health Across the Nation (SWAN), Black women reported a higher symptom burden than White women and were less likely to receive treatment.

Consistent screening narrows this gap. When every patient hears the same questions and the same full range of options, fewer women fall through. Insurance coverage for evidence-based treatment matters too, especially as misinformation about menopause spreads online.

Put it into practice

1

Ask

Screen every midlife patient for hot flashes, night sweats, sleep problems, and mood changes.

2

Assess

Review age, time since menopause, medical history, and baseline risks for heart disease, breast cancer, and blood clots.

3

Offer

Present hormonal, nonhormonal, and nonpharmacologic options. Decide together.

4

Follow up

Reassess at 3 months, adjust the plan, and revisit it each year.

What comes next

ACOG plans separate guidance on the genitourinary syndrome of menopause (GSM) in 2027. Vaginal dryness and urinary symptoms affect quality of life as much as hot flashes do. ACOOG will share updates and education as this guidance arrives.

Keep your menopause care current.

Earn CME on menopause and midlife care through ACOOG education.

Browse Related CME

References

  1. American College of Obstetricians and Gynecologists. Management of menopause-related vasomotor, sleep, and mood symptoms. Clinical Practice Guideline No. 13. Obstet Gynecol. 2026;148:e345-e369. View the guideline
  2. American College of Obstetricians and Gynecologists. ACOG expands recommendations for management of menopause symptoms. News release. October 15, 2026. Read the release

This article summarizes published clinical guidance for physicians and does not replace individual clinical judgment.

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